Open positions

Open positions: POST-DOCTORAL fellows in machine learning and bioinformatics

The Hoffman Lab at the Princess Margaret Cancer Centre and the University of Toronto (Canada) seeks new members for its team. We develop machine learning techniques to better understand chromatin biology. These models and algorithms transform high-dimensional functional genomics data into interpretable patterns and lead to new biological insight. A key focus of the lab is to train a new generation of computational biologists.

We seek postdoctoral fellows for several projects in computational genomics and machine learning. Selected projects include:
1. Integrating epigenomic and sequence data to better understand human gene regulation.
2. Creating models of transcription factor binding that allow us to predict the effects of perturbations.
3. Developing deep learning techniques to find novel behavior in multiple functional genomics datasets.
Required qualifications: Doctorate in computational biology, computer science, electrical engineering, statistics, or physics, obtained within the last five years. Submitted first-author or joint first-author papers in genomics or machine learning research. Experience in scientific programming in a Unix environment.

Preferred qualifications (not required): Experience with epigenomics and graphical models. Published first-author papers in peer-reviewed journals or refereed conference proceedings. Experience programming in Python, R, C, and C++.
To apply: We will accept applications until the positions are filled. Please submit your CV (as PDF file), your best paper (as PDF file), the URL of a code sample, and the names, email addresses, and phone numbers of three references to michael.hoffman(AT)

The Princess Margaret Cancer Centre is a teaching hospital and a scientific research institute, affiliated with the University of Toronto. It is located in Toronto Downtown and has the largest cancer research program in Canada. It is a component of the University Health Network, Canada’s largest clinical healthcare and biomedical scientific research organization.
The Hoffman Lab is part of a Centre for Cancer Epigenomics at the Princess Margaret Cancer Centre. There are ample opportunities for collaboration and scientific exchange with a large community of genomics, computational biology, and machine learning groups at the University of Toronto Department of Computer Science and associated institutions, such as the Hospital for Sick Children (SickKids).


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